Cardcaptor Sakura.

Then Fullmetal Alchemist.

NHK ni Youkoso! It touched me in a very deep way. ¦3

The ending of Bakuretsu Tenshi kind of wrenched my heart, but I didn't cry.

Edit: Oh, Golden Boy made me cry...with LAUGHTER. Funniest anime EVER.

I cried watching so many anime series before..

FMA (really sad when Nina and hughes died) :pinkcry:
X TV (it's very touching.. i just can't stop crying.. but not sure why i cry)
Toki wo Kakeru Shoujo (quite sad at the end)
TRC (Kurogane has such a sad past.. -sob sob-)
Hikaru no go (when Sai suddenly leaves...)

and many more..

If it's an RPG, the end of Final Fantasy X made me cry just a little more than the end of Kingdom Hearts, but not as half much as when Cloud laid Aerith to rest in that pool in Final Fantasy VII.

Waaaaah!!! :pinkcry:

Code geass when it ended and death note
jup those where it for me XD

I wouldnt say the anime so much... but the Fruits Basket manga really touched me. :(

The end of Code Geass got me too.

Elfen Lied for sure

then there was Chrono Crusade ending...

Code Geass: r2 finale

Fullmoon wo Sagashite...